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What is Orfidal

Orfidal is in a group of drugs called benzodiazepines. Orfidal affects chemicals in the brain that may become unbalanced and cause anxiety.
Orfidal is used to treat anxiety disorders.
Orfidal may also be used for other purposes not listed in Orfidal guide.

Orfidal side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Orfidal dosing

Usual Adult Dose for ICU Agitation:

IV, intermittent:
Initial dose: 1 to 4 mg IV every 10 to 20 minutes to Orfidal acute agitation.
Maintenance dose: 1 to 4 mg IV every 2 to 6 hours and as needed to maintain desired level of sedation.
IV, continuous infusion:
0.01 to 0.1 mg/kg/hr IV to maintain desired level of sedation.
High-dose infusions have been associated with tubular necrosis, lactic acidosis and hyperosmolality states due to the polyethylene glycol and propylene glycol solvents.

Usual Adult Dose for Anxiety:

Oral:
Initial dose: 1 mg orally 2 to 3 times a day.
Maintenance dose: 1 to 2 mg orally 2 to 3 times a day. The daily dosage may vary from 1 to 10 mg/day orally.
IV:
Alternatively, an initial intravenous dose of 2 mg or 0.044 mg/kg, whichever is smaller, may be given.

Usual Adult Dose for Insomnia:

2 to 4 mg orally at bedtime

Usual Adult Dose for Light Anesthesia:

Premedication for Anesthesia:
IM: 0.05 mg/kg up to a maximum of 4 mg.
IV: 2 mg total, or 0.044 mg/kg, whichever is smaller.
This dose should not ordinarily be exceeded in patients over 50 years of age.
Larger doses as high as 0.05 mg/kg up to a total of 4 mg may be administered.

Usual Adult Dose for Nausea/Vomiting:

Oral or IV: 0.5 to 2 mg every 4 to 6 hours as needed

Usual Adult Dose for Status Epilepticus:

4 mg/dose slow IV over 2 to 5 minutes ; may repeat in 10 to 15 minutes; usual total maximum dose: 8 mg

Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:

Children: IV: Limited information exists, especially for multiple doses:
Single dose: 0.04 to 0.08 mg/kg/dose prior to chemotherapy (maximum dose: 4 mg)
Multiple doses: Some centers use 0.02 to 0.05 mg/kg/dose (maximum dose: 2 mg) every 6 hours as needed

Usual Pediatric Dose for Anxiety:

Infants and Children: Usual: 0.05 mg/kg/dose every 4 to 8 hours; range: 0.02 to 0.1 mg/kg

Usual Pediatric Dose for Sedation:

Sedation (preprocedure): Infants and Children:
Oral, IM, IV: Usual: 0.05 mg/kg; range: 0.02 to 0.09 mg/kg
IV: May use smaller doses (e.g., 0.01 to 0.03 mg/kg) and repeat every 20 minutes, as needed to titrate to effect

Usual Pediatric Dose for Status Epilepticus:

Infants and Children: 0.05 to 0.1 mg/kg slow IV over 2 to 5 minutes (maximum rate: 2 mg/minute); may repeat every 10 to 15 minutes if needed.
Adolescents: 0.07 mg/kg (maximum: 4 mg/dose) slow IV over 2 to 5 minutes (maximum rate: 2 mg/minute); may repeat in 10 to 15 minutes if needed; usual total maximum dose: 8 mg.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
ALMAZINE tab 1 mg x 10's $0.18Psycorem
Almazine 2.5mg Tablet $0.04Psycormedies
1 mg10 $0.22
2 ml1 $0.21
ANXILOR 1MG TABLET 1 strip(s) (10 tablets each) $0.27Tas Med India Pvt Ltd
Anxilor 2mg Tablet $0.03Tas Med India Pvt Ltd
ANXILOR 2MG TABLET 1 strip(s) (10 tablets each) $0.46Tas Med India Pvt Ltd
Anxipose 0.5mg Tablet $0.02Psychotropics India Ltd
2 mg x 10's $0.20
Anxipose 0.5mg TAB / 10 $0.08
Atipam 1mg Tablet $0.02Ind Swift Laboratories Ltd
1 mg x 10's $0.18
ATIPAM tab 1 mg x 10's $0.18Ind-Swift
Atipam 1mg TAB / 10 $0.18
2 mg x 10's $0.22
ATIPAM tab 2 mg x 10's $0.22Ind-Swift
Atipam 2mg TAB / 10 $0.22
Atipam 2mg Tablet $0.04Ind Swift Laboratories Ltd
1 mg10 $0.15
Benj 1 mg Tablet $0.02
Benj 1mg Tablet $0.03Talent India
Benj 2mg Tablet $0.03Talent India
BENJ 1MG TABLET 1 strip(s) (10 tablets each) $0.28Talent Healthcare
BENJ 2MG TABLET 1 strip(s) (10 tablets each) $0.34Talent Healthcare
1 mg10 $0.11
2 mg10 $0.14
Biokalm 1 mg Tablet $0.01
Biokalm 2 mg Tablet $0.01
2 mg10 $0.13
2 mg x 10's $0.15
Calmese 2mg x 1mL AMP / 2ml $0.17
Calmese 1mg TAB / 10 $0.11
2 mg x 2ml $0.21
LORA inj 2 mg x 1 mL x 2ml $0.21Orchid (Psychiatry)
Lora 2mg AMP / 2ml $0.21
1 mg10 $0.15
Loracalm 1mg Tablet $0.02Torrent Pharmaceuticals Ltd
Loracalm 2mg Tablet $0.02Torrent Pharmaceuticals Ltd
1 mg x 10's $0.15
LORACALM 1MG TABLET 1 strip(s) (10 tablets each) $0.15Torrent Pharmaceuticals Ltd
LORACALM tab 1 mg x 10's $0.15Torrent
Loracalm 1mg TAB / 10 $0.15
LORACALM 2MG TABLET 1 strip(s) (10 tablets each) $0.21Torrent Pharmaceuticals Ltd
Loram 2.5 mg/50 mg Tablet $0.16Unichem Laboratories Ltd
Loram Capsule/ Tablet / 50mg-2.5mg (10 units) $0.95Unichem Laboratories (Unisearch Division)
Loram Losartan potassium 50 mg, Ramipril 5 mg. TAB / 10 $1.24
Lorax 1mg Tablet $0.01Consern Pharma P Ltd
Lorax 2mg Tablet $0.02Consern Pharma P Ltd
LORAX 1MG TABLET 1 strip(s) (10 tablets each) $0.15Consern Pharma P Ltd
LORAX 2MG TABLET 1 strip(s) (10 tablets each) $0.24Consern Pharma P Ltd
10 's $0.84
LORAX tab 10's $0.84Pax Healthcare
Lorax Lornoxicam 8 mg, Paracetamol500 mg. TAB / 10 $0.84
1 mg x 10's $0.21
LORAZAM tab 1 mg x 10's $0.21Invision (Marx)
Lorazam 1mg TAB / 10 $0.21
2 mg x 10's $0.36
LORAZAM tab 2 mg x 10's $0.36Invision (Marx)
Lorazam 2mg TAB / 10 $0.36
1 mg10 $0.11
LORAZINE 2MG TABLET 1 strip(s) (10 tablets each) $0.20Micro Labs Ltd
2 mg x 10's $0.15
Lorel 2mg Tablet $0.03Reliance Formulation Pvt Ltd
Lorel 1mg TAB / 10 $0.11
1 mg10 $0.18
LORIPAM inj 2 mg x 1 mL x 2ml $0.18Triton (Calyx)
LORIPAM sublingual tab 1 mg x 10's $0.20Triton (Calyx)
Loripam 1mg Tablet $0.04Triton Healthcare Pvt Ltd
LORIPAM sublingual tab 2 mg x 10's $0.28Triton (Calyx)
LORIPAM tab 1 mg x 10's $0.41Triton (Calyx)
LORIPAM 1MG TABLET 1 strip(s) (10 tablets each) $0.41Triton Healthcare Pvt Ltd
Loripam 2mg Tablet $0.05Triton Healthcare Pvt Ltd
LORIPAM 2MG TABLET 1 strip(s) (10 tablets each) $0.54Triton Healthcare Pvt Ltd
LORIPAM tab 2 mg x 10's $0.55Triton (Calyx)
1 mg x 10's $0.20
Orazep 2 mg Tablet $0.03
Renaquil 1 mg x 10 x 10's $14.80
1 ml $0.10
Trapex 2mg TAB / 10 $0.18
TRAPEX 2 MG TABLET 1 strip(s) (10 tablets each) $0.34Sun Pharma Laboratories Ltd
1 mg10 $0.17
Zepatrac 2 mg Tablet $0.04
2 mg x 10's $0.36
ZEPATRAC tab 2 mg x 10's $0.36Minova (Psychonova)
Zepatrac 2mg TAB / 10 $0.36
Zora 10mg Tablet $0.03Corona Remedies Pvt Ltd
ZORA 10MG TABLET 1 strip(s) (10 tablets each) $0.33Corona Remedies Pvt Ltd
Zora 20mg Tablet $0.06Corona Remedies Pvt Ltd
ZORA 20MG TABLET 1 strip(s) (10 tablets each) $0.63Corona Remedies Pvt Ltd
Zora 40mg Tablet $0.10Corona Remedies Pvt Ltd
ZORA 40MG TABLET 1 strip(s) (10 tablets each) $1.05Corona Remedies Pvt Ltd

References

  1. Dailymed."Lorazepam: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Lorazepam". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Lorazepam". http://www.drugbank.ca/drugs/DB0018... (accessed August 28, 2018).

Orfidal - Frequently asked Questions

Can Orfidal be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Orfidal?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Measure the liquid form of Orfidal with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Orfidal should be used for only a short time. Do not take this medication for longer than 4 months without your doctor's advice.

Orfidal may be habit-forming and should be used only by the person it was prescribed for. Orfidal should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Contact your doctor if this medicine seems to stop working as well in treating your symptoms.

Do not stop using Orfidal suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Your symptoms may return when you stop using Orfidal after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Orfidal. Withdrawal symptoms may include tremor, sweating, muscle cramps, stomach pain, vomiting, unusual thoughts or behavior, and seizure.

To be sure this medication is not causing harmful effects, your doctor may need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Orfidal at room temperature away from moisture, heat, and light.

Store the liquid form of Orfidal in the refrigerator.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Who should not take Orfidal?

It is dangerous to try and purchase Orfidal on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of Orfidal purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide.

Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to Orfidal or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking Orfidal, tell your doctor if you are allergic to any drugs, or if you have:

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. Orfidal can cause birth defects in an unborn baby. Do not use Orfidal without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth Orfidal while you are using this medication.

It is not known whether Orfidal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of Orfidal may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Orfidal.

Do not give this medication to a child younger than 12 years old.

What other drugs will affect Orfidal?

Before taking Orfidal, tell your doctor if you are using any of the following drugs:

This list is not complete and there may be other drugs that can interact with Orfidal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Can Orfidal be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Orfidal be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Orfidal, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Orfidal. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


Patient reported side effects

No survey data has been collected yet


Patient reported price estimates

No survey data has been collected yet


Two patients reported frequency of use

How often should I take Orfidal?
According to the survey, gmedication.com reported that users of Orfidal should take Once in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Patients%
Once in a day1
50.0%
4 times in a day1
50.0%


Two patients reported doses

What is the specific doses you have used?
Orfidal May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients%
1-5mg2
100.0%


One patient reported time for results

How long will I use Orfidal before I begin to notice the effect?
According to the report by users of gmedication.com, about 5 days and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Orfidal. However, if you wish to get the response of other users on the time effectiveness of using Orfidal kindly click here
Patients%
5 days1
100.0%


Patient reported administration

No survey data has been collected yet


Three patients reported age

Patients%
> 602
66.7%
30-451
33.3%


Patient reviews


There are no reviews yet. Be the first to write one!


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The information was verified by Dr. Vishal Pawar, MD Pharmacology