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What is Lorazine

Lorazine is in a group of drugs called benzodiazepines. Lorazine affects chemicals in the brain that may become unbalanced and cause anxiety.
Lorazine is used to treat anxiety disorders.
Lorazine may also be used for other purposes not listed in Lorazine guide.

Lorazine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Lorazine dosing

Usual Adult Dose for ICU Agitation:

IV, intermittent:
Initial dose: 1 to 4 mg IV every 10 to 20 minutes to Lorazine acute agitation.
Maintenance dose: 1 to 4 mg IV every 2 to 6 hours and as needed to maintain desired level of sedation.
IV, continuous infusion:
0.01 to 0.1 mg/kg/hr IV to maintain desired level of sedation.
High-dose infusions have been associated with tubular necrosis, lactic acidosis and hyperosmolality states due to the polyethylene glycol and propylene glycol solvents.

Usual Adult Dose for Anxiety:

Oral:
Initial dose: 1 mg orally 2 to 3 times a day.
Maintenance dose: 1 to 2 mg orally 2 to 3 times a day. The daily dosage may vary from 1 to 10 mg/day orally.
IV:
Alternatively, an initial intravenous dose of 2 mg or 0.044 mg/kg, whichever is smaller, may be given.

Usual Adult Dose for Insomnia:

2 to 4 mg orally at bedtime

Usual Adult Dose for Light Anesthesia:

Premedication for Anesthesia:
IM: 0.05 mg/kg up to a maximum of 4 mg.
IV: 2 mg total, or 0.044 mg/kg, whichever is smaller.
This dose should not ordinarily be exceeded in patients over 50 years of age.
Larger doses as high as 0.05 mg/kg up to a total of 4 mg may be administered.

Usual Adult Dose for Nausea/Vomiting:

Oral or IV: 0.5 to 2 mg every 4 to 6 hours as needed

Usual Adult Dose for Status Epilepticus:

4 mg/dose slow IV over 2 to 5 minutes ; may repeat in 10 to 15 minutes; usual total maximum dose: 8 mg

Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:

Children: IV: Limited information exists, especially for multiple doses:
Single dose: 0.04 to 0.08 mg/kg/dose prior to chemotherapy (maximum dose: 4 mg)
Multiple doses: Some centers use 0.02 to 0.05 mg/kg/dose (maximum dose: 2 mg) every 6 hours as needed

Usual Pediatric Dose for Anxiety:

Infants and Children: Usual: 0.05 mg/kg/dose every 4 to 8 hours; range: 0.02 to 0.1 mg/kg

Usual Pediatric Dose for Sedation:

Sedation (preprocedure): Infants and Children:
Oral, IM, IV: Usual: 0.05 mg/kg; range: 0.02 to 0.09 mg/kg
IV: May use smaller doses (e.g., 0.01 to 0.03 mg/kg) and repeat every 20 minutes, as needed to titrate to effect

Usual Pediatric Dose for Status Epilepticus:

Infants and Children: 0.05 to 0.1 mg/kg slow IV over 2 to 5 minutes (maximum rate: 2 mg/minute); may repeat every 10 to 15 minutes if needed.
Adolescents: 0.07 mg/kg (maximum: 4 mg/dose) slow IV over 2 to 5 minutes (maximum rate: 2 mg/minute); may repeat in 10 to 15 minutes if needed; usual total maximum dose: 8 mg.

Compare prices at online shops


StrengthQuantityPrice, USDCountry
Micro Labs Ltd. (B & B)
1 mg10 $0.11India


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References

  1. Dailymed."Lorazepam: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Lorazepam". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Lorazepam". http://www.drugbank.ca/drugs/DB0018... (accessed August 28, 2018).

Lorazine - Frequently asked Questions

Can Lorazine be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Lorazine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Measure the liquid form of Lorazine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Lorazine should be used for only a short time. Do not take this medication for longer than 4 months without your doctor's advice.

Lorazine may be habit-forming and should be used only by the person it was prescribed for. Lorazine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Contact your doctor if this medicine seems to stop working as well in treating your symptoms.

Do not stop using Lorazine suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Your symptoms may return when you stop using Lorazine after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Lorazine. Withdrawal symptoms may include tremor, sweating, muscle cramps, stomach pain, vomiting, unusual thoughts or behavior, and seizure.

To be sure this medication is not causing harmful effects, your doctor may need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Lorazine at room temperature away from moisture, heat, and light.

Store the liquid form of Lorazine in the refrigerator.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What other drugs will affect Lorazine?

Before taking Lorazine, tell your doctor if you are using any of the following drugs:

This list is not complete and there may be other drugs that can interact with Lorazine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Who should not take Lorazine?

It is dangerous to try and purchase Lorazine on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of Lorazine purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide.

Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to Lorazine or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking Lorazine, tell your doctor if you are allergic to any drugs, or if you have:

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. Lorazine can cause birth defects in an unborn baby. Do not use Lorazine without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth Lorazine while you are using this medication.

It is not known whether Lorazine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of Lorazine may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Lorazine.

Do not give this medication to a child younger than 12 years old.

Can Lorazine be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Lorazine be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Lorazine, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Lorazine. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology