Naloxone (Valtran) blocks or reverses the effects of opioid medication, including extreme drowsiness, slowed breathing, or loss of consciousness. An opioid is sometimes called a narcotic. Naloxone (Valtran) is used to treat a narcotic overdose in an emergency situation. This medicine should not be used in place of emergency medical care for an overdose. Naloxone (Valtran) is also used to help diagnose whether a person has used an overdose of an opioid. Naloxone (Valtran) may also be used for purposes not listed in Naloxone (Valtran) guide.
How is Naloxone given?
Naloxone (Valtran) is injected into a muscle, under the skin, or into a vein through an IV. The injection may be given by a healthcare provider, emergency medical provider, or a family member or caregiver who is trained to properly give a Naloxone (Valtran) injection. If you are a caregiver or family member giving a Naloxone (Valtran) injection, read all instructions when you first get this medicine. If provided, use the "trainer" device to practice giving an injection so you will know how to do it in an emergency. Ask your doctor or pharmacist if you have any questions. Be sure you know how to recognize the signs of an opioid overdose in the person you are caring for. Overdose symptoms may include:
slowed breathing, or no breathing;
very small or pinpoint pupils in the eyes;
slow heartbeats; or
extreme drowsiness, especially if you are unable to wake the person from sleep.
Even if you are not sure an opioid overdose has occurred, if the person is not breathing or is unresponsive, give the Naloxone (Valtran) injection right away and then seek emergency medical care. Do not assume that an overdose episode has ended if symptoms improve. You must get emergency help after giving a Naloxone (Valtran) injection. Naloxone (Valtran) injected into a muscle is given in the outer thigh. In an emergency, you may give an injection through the person's clothing. After injecting Naloxone (Valtran), stay with the person and watch for continued signs of overdose. You may need to give another injection every 2 to 3 minutes until emergency help arrives. Follow all medication instructions carefully. Each Naloxone (Valtran) is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting a dose. Store at room temperature away from moisture and heat. Keep the auto-injector in its outer case until you are ready to use it. Do not use the medicine if it has changed colors or has particles in it. Call your pharmacist for new medication.
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Naloxone (Valtran) side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Because Naloxone (Valtran) reverses opioid effects, this medicine may cause sudden withdrawal symptoms such as:
nausea, vomiting, diarrhea, stomach pain;
fever, sweating, body aches, weakness;
tremors or shivering, fast heart rate, pounding heartbeats, increased blood pressure;
feeling nervous, restless, or irritable;
goosebumps, shivering;
runny nose, yawning; or
(in babies younger than 4 weeks old) seizures, crying, stiffness, overactive reflexes.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Naloxone (Valtran) dosing
Usual Adult Dose for Opioid Overdose:
Initial dose: 0.4 mg to 2 mg IV; alternatively, may give IM or subcutaneously -If desired response is not obtained, doses should be repeated at 2 to 3 minute intervals -If no response is observed with a total dose of 10 mg, the diagnosis of opioid-induced or partial opioid-induced toxicity should be questioned Auto-injector: For emergency use in the home or other non-medical setting -Administer 0.4 mg IM or subcutaneously into the anterolateral aspect of the thigh (through clothing if necessary) -If desired response is not achieved, a second dose may be administered after 2 or 3 minutes; additional doses may be administered every 2 to 3 minutes until emergency medical assistance arrives Nasal Spray: -Administer 1 spray intranasally into 1 nostril -If desired response is not achieved after 2 or 3 minutes, give a second dose intranasally into alternate nostril; additional doses may be administered every 2 to 3 minutes in alternating nostrils until emergency medical assistance arrives Comments: -IV route is recommended in emergency situations since it has the most rapid onset of action. -The duration of action of some opioids exceed that of this drug, therefore, repeat doses may be needed; the need for repeat doses will depend on the amount, type, and route of administration of the opioid being antagonized. -Patients should remain under continued surveillance; if a patients responds and relapses back into respiratory depression, additional doses should be given. -Additional supportive and/or resuscitative measures may be helpful while awaiting emergency medical assistance. Use: For the emergency treatment of known or suspected opioid overdose as manifested by respiratory and/or central nervous system depression.
Usual Adult Dose for Reversal of Opioid Sedation:
Initial dose: 0.1 to 0.2 mg IV at 2 to 3 minute intervals to the desired degree of reversal -Supplemental doses administered IM have been shown to produce a longer lasting effect Intravenous Infusion: -A concentration of 0.004 mg/mL may be administered by IV infusion; titrate in accordance with patient's response Comments: -For the partial reversal of opioid depression following the use of opioids during surgery, smaller doses of Naloxone (Valtran) are usually sufficient; larger than necessary doses may result in significant reversal of analgesia and increases in blood pressure. Use: For the complete or partial reversal of opioid depression including respiratory depression, induced by natural and synthetic opioids and certain mixed agonist-antagonist analgesics.
Usual Pediatric Dose for Opioid Overdose:
Neonates: Initial dose: 0.01 mg/kg IV, IM, or subcutaneously; repeat dose every 2 to 3 minutes as needed Children: Initial dose: 0.01 mg/kg IV; if desired response is not obtained, may give 0.1 mg/kg IV -If IV route is not available may give IM or subcutaneously in divided doses Auto-injector: For emergency use in the home or other non-medical setting -Administer 0.4 mg IM or subcutaneously into the anterolateral aspect of the thigh (through clothing if necessary); if desired response is not achieved, a second dose may be administered after 2 or 3 minutes; additional doses may be administered every 2 to 3 minutes until emergency medical assistance arrives -Under 1 year of age: Thigh muscle should be pinched while administering injection Nasal Spray: -Administer 1 spray intranasally into 1 nostril -If desired response is not achieved after 2 or 3 minutes, give a second dose intranasally into alternate nostril; additional doses may be administered every 2 to 3 minutes in alternating nostrils until emergency medical assistance arrives Comments: -Neonatal opioid withdrawal syndrome may be life-threatening and should be treated according to protocols developed by neonatology experts. - To avoid precipitating opioid withdrawal symptoms, consider use of a Naloxone (Valtran) product that can be dosed according to weight and titrated to effect. -The duration of action of some opioids will exceed that of this drug, therefore, repeat doses may be needed; the need for repeat doses will depend on the amount, type, and route of administration of the opioid being antagonized. -Patients should remain under continued surveillance; if a patients responds and relapses back into respiratory depression, additional doses should be given. -Additional supportive and/or resuscitative measures may be helpful while awaiting emergency medical assistance. Use: For the emergency treatment of known or suspected opioid overdose as manifested by respiratory and/or central nervous system depression.
Usual Pediatric Dose for Reversal of Opioid Sedation:
Neonates: Initial dose: 0.01 mg/kg IV, IM or subcutaneously at 2 to 3 minute intervals to the desired degree of reversal Children: 0.005 mg to 0.01 mg IV at 2 to 3 minute intervals to the desired degree of reversal Intravenous Infusion: -A concentration of 0.004 mg/mL may be administered by IV infusion; titrate in accordance with patient's response Comments: -For the partial reversal of opioid depression following the use of opioids during surgery, smaller doses of Naloxone (Valtran) are usually sufficient; larger than necessary doses may result in significant reversal of analgesia and increases in blood pressure. Use: For the complete or partial reversal of opioid depression including respiratory depression, induced by natural and synthetic opioids and certain mixed agonist-antagonist analgesics.
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Valtran - Frequently asked Questions
Can Valtran be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
What other drugs will affect Naloxone (Valtran)?
Other drugs may interact with Naloxone (Valtran), including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.
Who should not take Naloxone (Valtran)?
You should not receive this medicine if you are allergic to Naloxone (Valtran).
To make sure Naloxone (Valtran) is safe for you, tell your doctor if you have:
heart disease.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether Naloxone (Valtran) passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
Can Valtran be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Valtran be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Valtran, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Valtran. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
Patient reports
Three patients reported useful
How active was the Valtran in relieving patients of the disease or symptoms? Based on the survey reports from users of gmedication.com, about Useful percentage of users claimed the Valtran were useful to them in reducing their symptoms and diseases. However, the effectiveness of the medicine is influenced by many factors like the perception of the symptom, the severity of the conditions, and some other factors; the brand name could also be a factor to an extent. In the event the medicine does not produce the same effective result in your case, ensure you consult your medical expert to reexamine you on your disease or symptoms and prescribe, after that, alternative medications.
Patients
%
Useful
2
66.7%
Not useful
1
33.3%
Two patients reported side effects
Does the Valtran Have Any Side Effects? Based on the survey report from users of gmedication.com, about No side effects number of people suffered some side effect after consumption of Valtran. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Valtran.
Patients
%
No side effects
1
50.0%
It has side effects
1
50.0%
Three patients reported price estimates
Do you think The Price of Valtran is Worth It? Do you feel you paid higher than the value you got from it after usage? According to reports from gmedication.com users, on whether the Valtran medicine is affordable, users shared different opinions on the question. The views concerning the price of the medicine were based on some factors like the brand the patient bought, the price compared to its level of effectiveness, the nation or country where the medicine is sold, and the amount of money the patient has. For users who are of the opinion that the medicine is unaffordable, they may have to consider a medicine with another brand in a bid to reduce cost.
Patients
%
Not expensive
2
66.7%
Expensive
1
33.3%
Four patients reported frequency of use
How often should I take Valtran? According to the survey, gmedication.com reported that users of Valtran should take Twice in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Patients
%
Twice in a day
4
100.0%
Thirteen patients reported doses
What is the specific doses you have used? Valtran May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients
%
51-100mg
5
38.5%
11-50mg
2
15.4%
1-5mg
2
15.4%
101-200mg
2
15.4%
6-10mg
1
7.7%
201-500mg
1
7.7%
Two patients reported time for results
How long will I use Valtran before I begin to notice the effect? According to the report by users of gmedication.com, about 1 week and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Valtran. However, if you wish to get the response of other users on the time effectiveness of using Valtran kindly click here
Patients
%
1 week
1
50.0%
2 days
1
50.0%
One patient reported administration
When is the best condition to take Valtran: Before or after food? Based on the survey, the users of gmedication.com voted that Valtran is best taken at With a meal. It is however worthy of mention that this popular vote may not be an appropriate description for your particular health condition. See your doctor for professional medical advice as regards the best time to take this medicine. If you wish to see the views of other users on the best time to take the medicine, simply click here.
Patients
%
With a meal
1
100.0%
Seven patients reported age
Patients
%
> 60
4
57.1%
46-60
2
28.6%
30-45
1
14.3%
Patient reviews
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