Managing weight in certain patients when used in combination with exercise and diet. Naltrexonhydrochloride PCH is a combination of 2 medicines used to control appetite. Exactly how it works is not known, but it is thought to help to release certain chemicals in the brain that control appetite.
Important safety information:
Follow the diet and exercise program given to you by your health care provider.
Check with your doctor before you drink alcohol or use medicines that may cause drowsiness while you are taking Naltrexonhydrochloride PCH; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Naltrexonhydrochloride PCH may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you use a lot of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Naltrexonhydrochloride PCH.
If you already drink alcohol or if you take barbiturates (eg, phenobarbital), benzodiazepines (eg, alprazolam), sedatives (medicines that make you sleepy), or seizure medicines, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.
The risk of seizures may be greater if you take Naltrexonhydrochloride PCH in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Naltrexonhydrochloride PCH for longer than prescribed without checking with your doctor.
If your doctor tells you to stop taking Naltrexonhydrochloride PCH, you will need to wait at least 14 days before beginning to take certain other medicines (eg, MAOIs). Ask your doctor when you should start to take your new medicines after you have stopped taking Naltrexonhydrochloride PCH.
Children, teenagers, and young adults who take Naltrexonhydrochloride PCH may be at increased risk of suicidal thoughts or actions. Watch all patients who take Naltrexonhydrochloride PCH closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
Talk with your doctor before you take opioid medicines (eg, certain cough and cold products, certain diarrhea medicines, certain pain relievers) while you are using Naltrexonhydrochloride PCH; you will not receive as much effect from these medicines. Do not try to overcome this effect by taking large doses of opioid medicines. Taking large doses of opioid medicines may cause serious injury, coma, or death. Discuss any questions or concerns with your doctor.
Patients who no longer take Naltrexonhydrochloride PCH may be more sensitive to opioids. Even low doses of opioids may cause serious and life-threatening effects in these patients. Discuss any questions or concerns with your doctor.
If you have been taking an opioid medicine for a long time, you may need to be opioid-free for at least 7 to 10 days before you start Naltrexonhydrochloride PCH. Discuss any questions or concerns with your doctor.
Some people may be at risk for eye problems from Naltrexonhydrochloride PCH. Your doctor may want you to have an eye exam to see if you are at risk for these eye problems. Call your doctor right away if you have eye pain, vision changes, or swelling or redness in or around the eye.
Naltrexonhydrochloride PCH may increase blood pressure or heart rate. Your doctor will monitor your blood pressure and heart rate while you are taking Naltrexonhydrochloride PCH.
A very bad skin reaction (Stevens-Johnson syndrome) has happened with Naltrexonhydrochloride PCH. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have symptoms like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
Diabetes patients - Naltrexonhydrochloride PCH may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Naltrexonhydrochloride PCH may interfere with certain lab tests, including urine screenings for amphetamines. Be sure your doctor and lab personnel know you are taking Naltrexonhydrochloride PCH.
Use Naltrexonhydrochloride PCH with caution in the ELDERLY; they may be more sensitive to its effects.
Naltrexonhydrochloride PCH should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Naltrexonhydrochloride PCH if you are pregnant. It may cause harm to the fetus. If you think you may be pregnant, contact your doctor right away. Naltrexonhydrochloride PCH is found in breast milk. Do not breast-feed while taking Naltrexonhydrochloride PCH.
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Naltrexonhydrochloride PCH side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; painful sores in the mouth or around the eyes; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; swollen lymph glands; unusual hoarseness); chest pain; confusion; delusions; fainting; fast or irregular heartbeat; hallucinations; muscle or joint pain; new or worsening mental, mood, or behavior changes (eg, concentration problems, depression, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being, inability to sit still); seizures; severe or persistent headache, dizziness, or drowsiness; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; slow or shallow breathing; suicidal thoughts or attempts; symptoms of liver problems (eg, dark urine, pale stools, nausea, persistent loss of appetite, severe stomach pain, yellowing or the skin or eyes).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Naltrexone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Naltrexonhydrochloride PCH be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Naltrexonhydrochloride PCH?
Some medical conditions may interact with Naltrexonhydrochloride PCH. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse or dependence
if you have diabetes, low blood oxygen levels, kidney problems, high blood pressure, or increased eye pressure or glaucoma
if you have a history of a condition that may increase the risk of seizures (eg, certain blood vessel problems in the brain, head injury, a tumor or infection in the brain or spinal cord, stroke), heart problems (eg, heart attack), low blood sugar levels, low blood sodium levels, or liver problems
if you drink alcohol
if you are taking a medicine that contains methylene blue
Some MEDICINES MAY INTERACT with Naltrexonhydrochloride PCH. Tell your health care provider if you are taking any other medicines, especially any of the following:
Antipsychotics (eg, haloperidol, risperidone), corticosteroids (eg, prednisone), insulin or oral medicines to treat diabetes (eg, glipizide), theophylline, tricyclic antidepressants (eg, amitriptyline), or other medicine that contains bupropion because the risk of seizures may be increased
Amantadine, clopidogrel, levodopa, linezolid, MAOIs (eg, phenelzine), or ticlopidine because they may increase the risk of naltrexone's side effects
Opioid medicines (eg, methadone) or partial opioid agonists (eg, buprenorphine) because their effectiveness may be decreased by Naltrexonhydrochloride PCH
Carbamazepine, efavirenz, lopinavir, phenobarbital, phenytoin, or ritonavir because they may decrease naltrexone's effectiveness
Amiloride, beta-blockers (eg, metoprolol, pindolol), certain antiarrhythmics (eg, flecainide, procainamide, propafenone), cimetidine, dopamine, famotidine, lorcaserin, memantine, metformin, oxaliplatin, phenothiazines (eg, thioridazine), ranitidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), tricyclic antidepressants (eg, nortriptyline), or varenicline because the risk of their side effects may be increased by Naltrexonhydrochloride PCH
This may not be a complete list of all interactions that may occur. Ask your health care provider if Naltrexonhydrochloride PCH may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How should I take Naltrexonhydrochloride PCH?
Use Naltrexonhydrochloride PCH as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Naltrexonhydrochloride PCH comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Naltrexonhydrochloride PCH refilled.
Take Naltrexonhydrochloride PCH by mouth with or without food. Avoid taking Naltrexonhydrochloride PCH with high-fat meals.
Swallow Naltrexonhydrochloride PCH whole. Do not break, crush, divide, or chew before swallowing. If you cannot swallow Naltrexonhydrochloride PCH whole, contact your doctor.
Continue to take Naltrexonhydrochloride PCH even if you feel well. Do not miss any doses.
If you miss a dose of Naltrexonhydrochloride PCH, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Naltrexonhydrochloride PCH.
Can Naltrexonhydrochloride PCH be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Naltrexonhydrochloride PCH be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Naltrexonhydrochloride PCH, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Naltrexonhydrochloride PCH. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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