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Metoprolol Axapharm retard |
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What is Metoprolol Axapharm retard
Metoprolol Axapharm retard is a beta-blocker that affects the heart and circulation.Metoprolol Axapharm retard is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.
Metoprolol Axapharm retard may also be used for other purposes not listed in Metoprolol Axapharm retard guide.
Metoprolol Axapharm retard side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have:
- very slow heartbeats;
- a light-headed feeling, like you might pass out;
- shortness of breath, swelling, rapid weight gain; or
- cold feeling in your hands and feet.
Common side effects may include:
- dizziness, tired feeling;
- confusion, memory problems;
- nightmares, trouble sleeping;
- diarrhea; or
- mild itching or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Metoprolol Axapharm retard dosing
Usual Adult Dose for Angina Pectoris Prophylaxis:
Initial dose: 100 mg orally in 1 or 2 divided doses.Maintenance dose: 100 to 450 mg/day.
Extended release may be used at the same total daily dose given once a day.
Usual Adult Dose for Hypertension:
Initial dose: 100 mg orally in 1 or 2 divided doses.Maintenance dose: 100 to 450 mg/day.
Extended release may be used at the same total daily dose given once a day.
Usual Adult Dose for Supraventricular Tachycardia:
Initial dose: 100 mg orally in 1 or 2 divided doses.Maintenance dose: 100 to 450 mg/day.
Extended release may be used at the same total daily dose given once a day.
Usual Adult Dose for Angina Pectoris:
Initial dose: 100 mg orally in 1 or 2 divided doses.Maintenance dose: 100 to 400 mg/day.
Extended release may be used at the same total daily dose given once a day.
Usual Adult Dose for Myocardial Infarction:
Early treatment:IV: 3 bolus injections of 5 mg of Metoprolol Axapharm retard given at 2 minute intervals.
Oral: In patients who tolerate the full IV dose, Metoprolol Axapharm retard tablets, 50 mg every 6 hours, should be initiated 15 minutes after the last IV dose and continued for 48 hours. Maintenance dose: 100 mg orally twice a day.
Patients who appear not to tolerate the full IV dose should be started on Metoprolol Axapharm retard tablets at 25 mg or 50 mg every 6 hours 15 minutes after the last intravenous dose or as soon as their clinical condition allows.
Late treatment:
Oral: 100 mg orally twice a day.
Patients with contraindications to treatment during the early phase of suspected or definite myocardial infarction, patients who appear not to tolerate the full early treatment, and patients in whom the physician wishes to delay therapy for any other reason should be started on Metoprolol Axapharm retard tablets as soon as their clinical condition allows.
Usual Adult Dose for Congestive Heart Failure:
Initial dose: 25 mg once daily (of the XL formulation) for two weeks in patients with NYHA class II heart failure and 12.5 mg once daily (of the XL formulation) in patients with more severe heart failure.Maintenance dose: This dosage should then be doubled every two weeks to the highest dosage level tolerated or up to 200 mg.
If transient worsening of heart failure occurs, it may be treated with increased doses of diuretics, and it may also be necessary to lower the dose or temporarily discontinue treatment. The dose should not be increased until symptoms of worsening heart failure stabilize.
Initial difficulty with titration should not preclude later attempts to institute therapy. If heart failure patients experience symptomatic bradycardia, the dose of Metoprolol Axapharm retard should be reduced.
Usual Pediatric Dose for Hypertension:
Immediate release:1 to 17 years:
Initial dose: 1 to 2 mg/kg/day, administered in 2 divided doses. Dosage should be adjusted based on patient response.
Maximum dose: 6 mg/kg/day
Extended release:
6 to 16 years:
Initial dose: 1 mg/kg orally once daily (not to exceed 50 mg once daily). The minimum available dose is one half of the 25 mg tablet.
Maintenance dose: Dosage should be adjusted according to blood pressure response. Doses above 2 mg/kg (or in excess of 200 mg) once daily have not been studied.
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References
- Dailymed."Metoprolol fumarate: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- "Metoprolol". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "Metoprolol". http://www.drugbank.ca/drugs/DB0026... (accessed August 28, 2018).
Metoprolol Axapharm retard - Frequently asked Questions
Can Metoprolol Axapharm retard be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
What other drugs will affect Metoprolol Axapharm retard?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Metoprolol Axapharm retard, especially:
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prazosin;
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terbinafine;
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an antidepressant--bupropion, clomipramine, desipramine, duloxetine, fluoxetine, fluvoxamine, paroxetine, sertraline;
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an ergot medicine--dihydroergotamine, ergonovine, ergotamine, methylergonovine;
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heart or blood pressure medications--amlodipine, clonidine, digoxin, diltiazem, dipyridamole, hydralazine, methyldopa, nifedipine, quinidine, reserpine, verapamil, and others;
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an MAO inhibitor--isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine; or
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medicine to treat mental illness--chlorpromazine, fluphenazine haloperidol, thioridazine.
This list is not complete. Other drugs may interact with Metoprolol Axapharm retard, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
How should I take Metoprolol Axapharm retard?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take the medicine at the same time each day.
Metoprolol Axapharm retard should be taken with a meal or just after a meal.
A Metoprolol Axapharm retard XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing.
While using Metoprolol Axapharm retard, you may need frequent blood tests at your doctor's office. Your blood pressure will need to be checked often.
If you need surgery, tell the surgeon ahead of time that you are using Metoprolol Axapharm retard.
You should not stop using Metoprolol Axapharm retard suddenly. Stopping suddenly may make your condition worse.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
Who should not take Metoprolol Axapharm retard?
You should not use this medication if you are allergic to Metoprolol Axapharm retard, or other beta-blockers, or if you have:
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a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate;
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severe circulation problems;
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severe heart failure (that required you to be in the hospital); or
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history of slow heart beats that have caused you to faint.
To make sure Metoprolol Axapharm retard is safe for you, tell your doctor if you have:
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asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;
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diabetes (taking Metoprolol Axapharm retard may make it harder for you to tell when you have low blood sugar);
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liver disease;
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congestive heart failure;
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problems with circulation (such as Raynaud's syndrome);
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a thyroid disorder; or
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pheochromocytoma (tumor of the adrenal gland).
It is not known whether Metoprolol Axapharm retard will harm an unborn baby. Tell your doctor right away if you become pregnant while using this medicine.
Metoprolol Axapharm retard can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Metoprolol Axapharm retard is not approved for use by anyone younger than 18 years old.
Can Metoprolol Axapharm retard be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Metoprolol Axapharm retard be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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The information was verified by Dr. Vishal Pawar, MD Pharmacology