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What is Trileptal 300 MG per 5 ML Oral Suspension

Trileptal 300 MG per 5 ML Oral Suspension is an anticonvulsant, or antiepileptic drug. It works by decreasing nerve impulses that cause seizures.
Trileptal 300 MG per 5 ML Oral Suspension is used either alone or with other medicines to treat partial seizures.
The Trileptal 300 MG per 5 ML Oral Suspension brand of Trileptal 300 MG per 5 ML Oral Suspension is used as a single medicine in adults and children who are at least 4 years old. Trileptal 300 MG per 5 ML Oral Suspension is used with other medicines in adults and children who are at least 2 years old.
The Trileptal 300 MG per 5 ML Oral Suspension brand of Trileptal 300 MG per 5 ML Oral Suspension is used with other medicines in adults and children who are at least 6 years old.
Trileptal 300 MG per 5 ML Oral Suspension may also be used for purposes not listed in Trileptal 300 MG per 5 ML Oral Suspension guide.

Trileptal 300 MG per 5 ML Oral Suspension side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Trileptal 300 MG per 5 ML Oral Suspension can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Call your doctor right away if you have headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, confusion, hallucinations, fainting, shallow breathing, and/or increased or more severe seizures.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive, or have thoughts about suicide or hurting yourself.
Also call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Trileptal 300 MG per 5 ML Oral Suspension dosing

Usual Adult Dose for Epilepsy:

Monotherapy:
Initiation of monotherapy:
Immediate-release:
Initial dose: 300 mg orally twice a day, increased by increments of 300 mg per day every third day as clinically indicated
Maintenance dose: 300 to 1,200 mg orally twice a day
Maximum dose: 1,200 mg orally twice a day
Conversion to monotherapy:
Immediate-release:
Initial dose: 300 mg orally twice a day, increased by increments of up to 600 mg per day at approximately weekly intervals as clinically indicated
Maintenance dose: 300 to 1,200 mg orally twice a day
Maximum dose: 1,200 mg orally twice a day
Comments:
-When converting to Trileptal 300 MG per 5 ML Oral Suspension monotherapy, concomitant antiepileptics should be completely withdrawn over 3 to 6 weeks, while a maximum dose should be reached in about 2 to 4 weeks.
-Patients should be closely observed during the transition from adjunctive to monotherapy with Trileptal 300 MG per 5 ML Oral Suspension.
Adjunctive Therapy:
Immediate-release:
Initial dose: 300 mg orally twice a day, increased by increments of up to 600 mg per day at approximately weekly intervals as clinically indicated
Maintenance dose: 300 mg to 1,200 mg orally twice a day
Maximum dose: 1,200 mg orally twice a day
Extended-release:
Initial dose: 600 mg orally once a day for one week, increased by increments of 600 mg per day at weekly intervals as clinically indicated
Maintenance dose: 1,200 to 2,400 mg orally once a day
Maximum dose: 2,400 mg orally once a day
Comments:
-Immediate release: Plasma levels of concomitant antiepileptic drugs should be monitored during titration of Trileptal 300 MG per 5 ML Oral Suspension. In controlled trials, most patients were not able to tolerate a dose of 2,400 mg per day, mainly due to CNS effects.
-Extended-release: A dose of 2,400 mg per day showed slightly greater efficacy than 1,200 mg per day; however, it was associated with an increased risk of side effects.
Use: Monotherapy or adjunctive therapy for the treatment of partial seizures; extended-release oral tablets are only indicated as adjunctive therapy.

Usual Geriatric Dose for Epilepsy:

Extended-release:
Initial dose: 300 to 450 mg orally once a day, increased by increments of 300 to 450 mg per day at weekly intervals as clinically indicated.
Use(s): Extended-release oral tablets are only indicated as adjunctive therapy for the treatment of partial seizures

Usual Pediatric Dose for Epilepsy:

Monotherapy:
4 to 16 years of age:
Immediate-release:
Initiation of monotherapy: 4 to 5 mg/kg orally twice a day, increased by an increment of 5 mg/kg per day every third day as clinically indicated
Conversion to monotherapy: 4 to 5 mg/kg orally twice a day (up to 600 mg per day), increased by an increment of 10 mg/kg per day at approximately weekly intervals as clinically indicated
Maintenance dose:
Body weight:
20 kg: 300 to 450 mg orally twice a day
25 to 30 kg: 450 to 600 mg orally twice a day
35 to 40 kg: 450 to 750 mg orally twice a day
45 kg: 600 to 750 mg orally twice a day
50 to 55 kg: 600 to 900 mg orally twice a day
60 to 65 kg: 600 to 1,050 mg orally twice a day
70 kg: 750 to 1,050 mg orally twice a day
Comments:
-When converting to Trileptal 300 MG per 5 ML Oral Suspension monotherapy, concomitant antiepileptics may be completely withdrawn over 3 to 6 weeks.
-Patients should be closely observed during the transition phase.
Adjunctive therapy:
2 to 4 years of age:
Immediate-release:
Initial dose:
Body weight:
20 kg or more: 4 to 5 mg/kg orally twice a day (up to 600 mg per day)
Less than 20 kg: 8 to 10 mg/kg orally twice a day
Maximum dose: 30 mg/kg orally twice a day
Comments:
-The maximum recommended dose should be achieved over 2 to 4 weeks
4 to 16 years of age:
Immediate-release:
Initial dose: 4 to 5 mg/kg orally twice a day (up to 600 mg per day)
Maintenance dose:
Body weight:
20 to 29 kg: 900 mg orally per day
29.1 to 39 kg: 1,200 mg orally per day
Greater than 39 kg: 1,800 mg orally per day
Comments:
-The target maintenance dose should be achieved over 2 weeks
6 to 17 years of age:
Extended-release:
Initial dose: 8 to 10 mg/kg (up to 600 mg) orally once a day, increased by an increment of 8 to 10 mg/kg per day (up to 600 mg) at weekly intervals if clinically indicated
Maintenance dose:
Body weight:
20 to 29 kg: 900 mg orally once a day
29.1 to 39 kg: 1,200 mg orally once a day
Greater than 39 kg: 1,800 mg orally once a day
Comments:
-Use is not recommended in patients younger than 6 years of age due to tablet size; data are not available in patients younger than 4 years of age.
Use(s): Monotherapy for the treatment of partial seizures in children 4 to 16 years; adjunctive therapy for the treatment of partial seizures in children 2 to 16 years; extended-release oral tablets are only indicated as adjunctive therapy.

Select the most affordable brand or generic drug


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OXANA film-coated tab 150 mg x 10's $0.48Psycorem
Oxana 300mg Tablet $0.09Psycormedies
Oxcarb 450mg Tablet $0.16Cipla Ltd
OXCARB Capsule/ Tablet / 150mg (10 units) $0.38Cipla (Protec Division)
OXCARB Capsule/ Tablet / 300mg (10 units) $0.67Cipla (Protec Division)
OXCARB film-coated tab 300 mg x 10's $0.98Cipla
Oxcarb 600mg FC-TAB / 10 $1.26
150 mg60 $92.00
150 mg100 $32.00Canada, India, NZ, Singapore, Turkey, UK, USA
150 mg100 $32.16Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
150 mg100 $34.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
150 mg100 $40.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
300 mg100 $42.00Canada, India, NZ, Singapore, Turkey, UK, USA
300 mg100 $42.21Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
300 mg100 $53.46Australia, Canada, NZ, Singapore, Turkey, UK, USA
300 mg100 $54.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
600 mg50 $150.36Canada, UK
600 mg100 $64.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
600 mg100 $68.00Canada, India, NZ, Singapore, Turkey, UK, USA
600 mg100 $68.34Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
600 mg100 $74.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
Trileptal 300 mg/5ml Suspension $0.79
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OXEP tab 150 mg x 10's $0.37AHPL
OXEP 300MG TABLET 1 strip(s) (10 tablets each) $0.68Abbott India Ltd
OXEP tab 600 mg x 10's $1.34AHPL
OXETOL Capsule/ Tablet / 600mg (10 units) $1.50Sun Pharmaceuticals
Oxetol 600 mg Tablet $0.18
OXETOL 450 MG TABLET XR 1 strip(s) (10 tablet xrs each) $1.89Sun Pharma Laboratories Ltd
Oxetol 150mg TAB / 10 $0.38
150 mg x 10's $0.51
OXETOL 150 MG TABLET XR 1 strip(s) (10 tablet xrs each) $0.77Sun Pharma Laboratories Ltd
Oxetol 300mg FC-TAB / 10 $0.92
OXETOL Capsule/ Tablet / 450mg (10 units) $1.34Sun Pharmaceuticals
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450 mg10 Tablet$1.05
Oxital 150 mg Tablet $0.05
Oxital 300 mg Tablet $0.07
Oxital 450 mg Tablet $0.10
Oxital 600 mg Tablet $0.13
150 mg10 Tablet$0.48
300 mg10 Tablet$0.88
600 mg x 10's $1.62
Oxmazetol-SR 600mg SR-TAB / 10 $1.62
150 mg x 10's $0.48
Oxmazetol-SR 150mg SR-TAB / 10 $0.48
300 mg x 10's $0.88
Oxmazetol-SR 300mg SR-TAB / 10 $0.88
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Selzic 450mg Tablet $0.18Sun Pharmaceutical Industries Ltd
Selzic 600mg Tablet $0.25Sun Pharmaceutical Industries Ltd
Selzic 150mg TAB / 10 $0.46
SELZIC 150 MG TABLET 1 strip(s) (10 tablets each) $0.70Ranbaxy Laboratories Ltd
Selzic 300 mg Tablet $0.11
SELZIC 300 MG TABLET 1 strip(s) (10 tablets each) $1.29Ranbaxy Laboratories Ltd
300 mg10 Tablet$0.70
Zepox 25mg Tablet $0.04Mayflower India
Zepox 150 mg Tablet $0.04
Zepox 150mg TAB / 10 $0.42
Zepox 300 mg Tablet $0.07
Zepox 300mg TAB / 10 $0.70
Zepox 450 mg Tablet $0.10
Zepox 450mg TAB / 10 $1.02
Zepox 600 mg Tablet $0.14
Zepox 600mg TAB / 10 $1.37
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References

  1. Dailymed."Oxcarbazepine: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."Trileptal (oxcarbazepine) tablet, film coated trileptal (oxcarbazepine) suspension [novartis pharmaceuticals corporation]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "Oxcarbazepine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Trileptal 300 MG per 5 ML Oral Suspension - Frequently asked Questions

Can Trileptal 300 MG per 5 ML Oral Suspension be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Trileptal 300 MG per 5 ML Oral Suspension?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Shake the oral suspension well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Give the liquid directly from the oral syringe, or mix the medicine with a small glass of water. After using the syringe, rinse it with water and allow it to air dry.

You may take the Trileptal 300 MG per 5 ML Oral Suspension oral liquid or regular tablet with or without food.

Take the Trileptal 300 MG per 5 ML Oral Suspension extended-release tablet (Oxtellar XR) on an empty stomach, at least 1 hour before or 2 hours after a meal.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Do not stop using Trileptal 300 MG per 5 ML Oral Suspension suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Get your prescription refilled before you run out of medicine completely.

While using Trileptal 300 MG per 5 ML Oral Suspension, you may need frequent blood tests.

Wear a medical alert tag or carry an ID card stating that you take Trileptal 300 MG per 5 ML Oral Suspension. Any medical care provider who treats you should know that you are using Trileptal 300 MG per 5 ML Oral Suspension.

Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Store at room temperature away from moisture and heat. Throw away any unused liquid 7 weeks after opening the bottle.

What other drugs will affect Trileptal 300 MG per 5 ML Oral Suspension?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking Trileptal 300 MG per 5 ML Oral Suspension with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety or depression.

Many other drugs can interact with Trileptal 300 MG per 5 ML Oral Suspension. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you. Not all possible interactions are listed in this medication guide.

Who should not take Trileptal 300 MG per 5 ML Oral Suspension?

You should not take this medicine if you are allergic to Trileptal 300 MG per 5 ML Oral Suspension.

To make sure Trileptal 300 MG per 5 ML Oral Suspension is safe for you, tell your doctor if you have:

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Trileptal 300 MG per 5 ML Oral Suspension. Your family or other caregivers should also be alert to changes in your mood or symptoms.

FDA pregnancy category C. Do not start or stop taking Trileptal 300 MG per 5 ML Oral Suspension during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking Trileptal 300 MG per 5 ML Oral Suspension for seizures.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Trileptal 300 MG per 5 ML Oral Suspension on the baby.

Trileptal 300 MG per 5 ML Oral Suspension can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking Trileptal 300 MG per 5 ML Oral Suspension.

Trileptal 300 MG per 5 ML Oral Suspension can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Trileptal 300 MG per 5 ML Oral Suspension.

Do not give this medicine to a child without medical advice. There are specific age restrictions for the use of Trileptal 300 MG per 5 ML Oral Suspension in children, depending on the dose form and whether it is used alone or with other medicines.

Can Trileptal 300 MG per 5 ML Oral Suspension be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Trileptal 300 MG per 5 ML Oral Suspension be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology