Treating low blood platelets in certain patients. It is also used to treat aplastic anemia in certain patients. Rebozet is a thrombopoietin receptor agonist. It works by causing the bone marrow to produce more cells.
Important safety information:
If you stop taking Rebozet, the number of clot-forming cells in your blood may return to a similar low platelet count as before you started taking Rebozet. Low blood platelets may increase your risk of bleeding, especially if you are also taking certain other medicines (eg, anticoagulants such as warfarin, antiplatelet medicines such as clopidogrel). These effects are most likely to occur within 4 weeks after you stop taking Rebozet. Your doctor will check your blood platelet counts for at least 4 weeks after you stop taking Rebozet. Tell your doctor if you have unusual bruising or bleeding after you stop taking Rebozet. Avoid activities that may cause bruising or injury. Discuss any questions or concerns with your doctor.
Do not change your dose of Rebozet without checking with your doctor.
Tell your doctor or dentist that you take Rebozet before you receive any medical or dental care, emergency care, or surgery.
Blood clots have occurred in patients taking Rebozet. Some blood clots (eg, those that cause heart attacks or strokes) have been fatal. The risk of developing a blood clot may be greater if you have a high number of clot-forming cells (platelets) in the blood. However, blood clots have occurred in patients with normal or low blood platelet levels. Tell your doctor immediately if you notice any signs of a blood clot (eg, pain, redness, tenderness, or swelling in the legs; chest pain; shortness of breath; coughing up blood).
Lab tests, including liver function, complete blood cell counts, and eye exams, may be performed while you use Rebozet and for at least 4 weeks after you stop Rebozet. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Rebozet with caution in patients of East Asian ancestry (eg, Chinese, Japanese, Taiwanese, Korean) and in patients who have moderate to severe liver problems. They may be more sensitive to the medicine and may require a lower dose than other patients. Discuss any questions or concerns with your doctor.
PREGNANCY and BREAST-FEEDING: It is not known if Rebozet can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Rebozet while you are pregnant. It is not known if Rebozet is found in breast milk. Do not breast-feed while taking Rebozet.
Rebozet side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Back pain; cough; diarrhea; dizziness; hair loss; joint pain; mild flu-like symptoms (eg, fever, headache, tiredness, sore throat, body aches); mild loss of appetite; minor muscle aches or pain; muscle spasms; nausea; symptoms of upper respiratory tract infection (eg, runny or stuffy nose, sneezing); trouble sleeping; vomiting; weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning with urination; chest pain; coughing up blood; frequent, painful, or urgent urination; new or worsening vision problems (eg, cloudy vision); pain or swelling in your throat or mouth; pain, redness, tenderness, or swelling in the legs; severe or persistent nausea, vomiting, or diarrhea; severe or persistent tiredness or weakness; shortness of breath; stomach pain; swelling of the hands, ankles, or feet; symptoms of heart attack (eg, chest, jaw, or arm pain; sudden, severe nausea or vomiting; unusual sweating; fainting); symptoms of new or worsening liver problems (eg, confusion, dark urine, persistent loss of appetite, pale stools, stomach pain or swelling, yellowing of the skin or eyes); symptoms of stroke (eg, confusion, slurred speech, sudden vision changes, one-sided weakness); unusual bruising or bleeding; unusual burning, itching, numbness, or tingling of the skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Eltrombopag olamine: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Rebozet be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
How should I take Rebozet?
Use Rebozet as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Rebozet comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Rebozet refilled.
Take Rebozet by mouth on an empty stomach at least 1 hour before or 2 hours after a meal.
Take Rebozet at least 4 hours before or 4 hours after you take certain other medicines (eg, antacids), calcium-rich foods (eg, dairy products, calcium-fortified juices), or supplements that contain iron, calcium, aluminum, magnesium, selenium, or zinc.
Do not suddenly stop taking Rebozet. You may have an increased risk of severe low platelets and bleeding. If you need to stop Rebozet, your doctor will need to monitor your condition.
If you miss a dose of Rebozet, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Do not take more than 1 dose in 1 day.
Ask your health care provider any questions you may have about how to use Rebozet.
Who should not take Rebozet?
Some medical conditions may interact with Rebozet. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of liver or kidney problems, cataracts, bleeding problems, or bone marrow problems, or if you have had surgery to remove your spleen
if you have a blood clot or a history of blood clots, a high number of clot-forming cells in the blood, or a condition that may increase your risk of getting a blood clot (eg, antithrombin III deficiency, antiphospholipid syndrome, Factor V Leiden)
if you use tobacco products
if you take a blood thinner (eg, warfarin) or an antiplatelet medicine (eg, clopidogrel)
if you are of East Asian ancestry (eg, Chinese, Japanese, Taiwanese, Korean)
Some MEDICINES MAY INTERACT with Rebozet. Tell your health care provider if you are taking any other medicines, especially any of the following:
Ciprofloxacin, fluvoxamine, gemfibrozil, or trimethoprim because they may increase the risk of eltrombopag's side effects
Omeprazole or rifampin because they may decrease eltrombopag's effectiveness
Acetaminophen, benzylpenicillin, bosentan, doxorubicin, ezetimibe, glyburide, statins (eg, atorvastatin, rosuvastatin), imatinib, irinotecan, lapatinib, meglitinides (eg, nateglinide, repaglinide), methotrexate, mitoxantrone, narcotic pain medications (eg, codeine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), olmesartan, sulfasalazine, topotecan, or valsartan because the risk of their side effects may be increased by Rebozet
This may not be a complete list of all interactions that may occur. Ask your health care provider if Rebozet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Can Rebozet be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Rebozet be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
Reviews
Following the study conducted by gmedication.com on Rebozet, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Rebozet. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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