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What is Gastonorm

Gastonorm increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.
Gastonorm is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.
Gastonorm is also used to treat slow gastric emptying in people with diabetes, which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals.
Gastonorm may also be used for purposes not listed in Gastonorm guide.

Gastonorm side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking Gastonorm and call your doctor at once if you have any of these SIGNS OF A SERIOUS MOVEMENT DISORDER, which may occur within the first 2 days of treatment:

Stop taking Gastonorm and call your doctor at once if you have any of these other serious side effects:


Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Gastonorm dosing

Usual Adult Dose for Nausea/Vomiting:

Postoperative nausea and vomiting:
Parenteral: 10 to 20 mg IM at or near the end of surgery

Usual Adult Dose for Gastroesophageal Reflux Disease:

Oral: 10 to 15 mg up to 4 times a day 30 minutes before meals and at bedtime, depending upon symptoms being treated and clinical response. Therapy should not exceed 12 weeks.

Usual Adult Dose for Small Intestine Intubation:

If the tube has not passed the pylorus with conventional methods in 10 minutes, a single dose may be administered IV slowly over 1 to 2 minutes:
Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes.

Usual Adult Dose for Radiographic Exam:

Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes to facilitate gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.

Usual Adult Dose for Gastroparesis:

During the earliest manifestations of diabetic gastric stasis, oral administration may be initiated. If severe symptoms are present, therapy should begin with IM or IV administration for up to 10 days until symptoms subside at which time the patient can be switched to oral therapy. Since diabetic gastric stasis is often recurrent, therapy should be reinstituted at the earliest manifestation.
Parenteral: 10 mg 4 times daily, IV or IM for up to 10 days.
Oral: 10 mg 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks depending on clinical response.

Usual Adult Dose for Nausea/Vomiting -- Chemotherapy Induced:

IV infusion: 1 to 2 mg/kg/dose (depending on the emetogenic potential of the agent) IV (infused over a period of not less than 15 minutes) 30 minutes before administration of chemotherapy. The dose may be repeated twice at 2 hour intervals following the initial dose. If vomiting is still not suppressed, the same dose may be repeated 3 more times at 3 hour intervals.
For doses higher than 10 mg, the injection should be diluted in 50 mL of a parenteral solution. Normal saline is the preferred diluent.
If acute dystonic reactions occur, 50 mg of diphenhydramine hydrochloride may be injected IM.

Usual Adult Dose for Migraine:

Use for treatment of migraine headaches is not an FDA approved indication; however, Gastonorm has shown efficacy in studies at a dose of 10 to 20 mg IV once.

Usual Pediatric Dose for Gastroesophageal Reflux Disease:

Gastonorm is not approved by the FDA for gastroesophageal reflux disease in pediatric patients; however, the following doses have been studied:
Oral, IM, IV:
Infants and Children: 0.4 to 0.8 mg/kg/day in 4 divided doses

Usual Pediatric Dose for Small Intestine Intubation:

Gastonorm IV is approved by the FDA for pediatric use to facilitate small bowel intubation by causing gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.
If the tube has not passed the pylorus with conventional methods in 10 minutes, a single dose may be administered IV slowly over 1 to 2 minutes:
Less than 6 years: 0.1 mg/kg IV as a single dose
6 to 14 years: 2.5 to 5 mg IV as a single dose
Children greater than 14 years: 10 mg as a single dose

Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:

Gastonorm is not approved by the FDA for chemotherapy induced nausea and vomiting in pediatric patients; however, the following doses have been studied:
IV:
1 to 2 mg/kg/dose IV 30 minutes before chemotherapy and every 2 to 4 hours

Usual Pediatric Dose for Nausea/Vomiting -- Postoperative:

Gastonorm is not approved by the FDA for postoperative nausea and vomiting in pediatric patients; however, the following doses have been studied:
IV:
Children less than or equal to 14 years: 0.1 to 0.2 mg/kg/dose ; repeat every 6 to 8 hours as needed
Children greater than 14 years and Adults: 10 mg; repeat every 6 to 8 hours as needed

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References

  1. "Metoclopramide". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  2. "Metoclopramide". http://www.drugbank.ca/drugs/DB0123... (accessed August 28, 2018).
  3. "L4yeb44i46: the unique ingredient identifier (unii) is an alphanumeric substance identifier from the joint fda/usp substance registration system (srs).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Gastonorm - Frequently asked Questions

Can Gastonorm be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

How should I take Gastonorm?

Take exactly as prescribed by your doctor. Gastonorm is usually taken for only 4 to 12 weeks. Follow the directions on your prescription label.

NEVER TAKE Gastonorm IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use of Gastonorm can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you take Gastonorm, the more likely you are to develop a serious movement disorder. The risk of this side effect is higher in women, diabetics, and older adults.

Take Gastonorm 30 minutes before eating. Gastonorm is usually taken before meals and at bedtime. Your doctor may want you to take the medication as needed only with meals that usually cause heartburn. Follow your doctor's instructions.

Measure the liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take Gastonorm orally disintegrating tablet (ODT):

Do not take two different forms of Gastonorm (such as tablets and oral syrup) at the same time.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

After you stop taking Gastonorm, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Who should not take Gastonorm?

You should not take this medication if you are allergic to Gastonorm, or if you have:

To make sure you can safely take Gastonorm, tell your doctor if you have any of these other conditions:

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Gastonorm can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The Gastonorm orally disintegrating tablet (ODT) may contain phenylalanine. Talk to your doctor before using this form of Gastonorm if you have phenylketonuria (PKU).

Gastonorm should not be given to a child.

What other drugs will affect Gastonorm?

Before using Gastonorm, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Gastonorm.

Tell your doctor about all other medications you use, especially:

This list is not complete and there are many other drugs that can interact with Gastonorm. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Can Gastonorm be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Gastonorm be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Gastonorm, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Gastonorm. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology