Managing weight in certain patients when used in combination with exercise and diet. Dependex is a combination of 2 medicines used to control appetite. Exactly how it works is not known, but it is thought to help to release certain chemicals in the brain that control appetite.
Important safety information:
Follow the diet and exercise program given to you by your health care provider.
Check with your doctor before you drink alcohol or use medicines that may cause drowsiness while you are taking Dependex; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Dependex may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you use a lot of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Dependex.
If you already drink alcohol or if you take barbiturates (eg, phenobarbital), benzodiazepines (eg, alprazolam), sedatives (medicines that make you sleepy), or seizure medicines, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.
The risk of seizures may be greater if you take Dependex in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Dependex for longer than prescribed without checking with your doctor.
If your doctor tells you to stop taking Dependex, you will need to wait at least 14 days before beginning to take certain other medicines (eg, MAOIs). Ask your doctor when you should start to take your new medicines after you have stopped taking Dependex.
Children, teenagers, and young adults who take Dependex may be at increased risk of suicidal thoughts or actions. Watch all patients who take Dependex closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
Talk with your doctor before you take opioid medicines (eg, certain cough and cold products, certain diarrhea medicines, certain pain relievers) while you are using Dependex; you will not receive as much effect from these medicines. Do not try to overcome this effect by taking large doses of opioid medicines. Taking large doses of opioid medicines may cause serious injury, coma, or death. Discuss any questions or concerns with your doctor.
Patients who no longer take Dependex may be more sensitive to opioids. Even low doses of opioids may cause serious and life-threatening effects in these patients. Discuss any questions or concerns with your doctor.
If you have been taking an opioid medicine for a long time, you may need to be opioid-free for at least 7 to 10 days before you start Dependex. Discuss any questions or concerns with your doctor.
Some people may be at risk for eye problems from Dependex. Your doctor may want you to have an eye exam to see if you are at risk for these eye problems. Call your doctor right away if you have eye pain, vision changes, or swelling or redness in or around the eye.
Dependex may increase blood pressure or heart rate. Your doctor will monitor your blood pressure and heart rate while you are taking Dependex.
A very bad skin reaction (Stevens-Johnson syndrome) has happened with Dependex. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have symptoms like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
Diabetes patients - Dependex may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Dependex may interfere with certain lab tests, including urine screenings for amphetamines. Be sure your doctor and lab personnel know you are taking Dependex.
Use Dependex with caution in the ELDERLY; they may be more sensitive to its effects.
Dependex should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Dependex if you are pregnant. It may cause harm to the fetus. If you think you may be pregnant, contact your doctor right away. Dependex is found in breast milk. Do not breast-feed while taking Dependex.
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Dependex side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; painful sores in the mouth or around the eyes; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; swollen lymph glands; unusual hoarseness); chest pain; confusion; delusions; fainting; fast or irregular heartbeat; hallucinations; muscle or joint pain; new or worsening mental, mood, or behavior changes (eg, concentration problems, depression, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being, inability to sit still); seizures; severe or persistent headache, dizziness, or drowsiness; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; slow or shallow breathing; suicidal thoughts or attempts; symptoms of liver problems (eg, dark urine, pale stools, nausea, persistent loss of appetite, severe stomach pain, yellowing or the skin or eyes).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Naltrexone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Dependex be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Dependex?
Some medical conditions may interact with Dependex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse or dependence
if you have diabetes, low blood oxygen levels, kidney problems, high blood pressure, or increased eye pressure or glaucoma
if you have a history of a condition that may increase the risk of seizures (eg, certain blood vessel problems in the brain, head injury, a tumor or infection in the brain or spinal cord, stroke), heart problems (eg, heart attack), low blood sugar levels, low blood sodium levels, or liver problems
if you drink alcohol
if you are taking a medicine that contains methylene blue
Some MEDICINES MAY INTERACT with Dependex. Tell your health care provider if you are taking any other medicines, especially any of the following:
Antipsychotics (eg, haloperidol, risperidone), corticosteroids (eg, prednisone), insulin or oral medicines to treat diabetes (eg, glipizide), theophylline, tricyclic antidepressants (eg, amitriptyline), or other medicine that contains bupropion because the risk of seizures may be increased
Amantadine, clopidogrel, levodopa, linezolid, MAOIs (eg, phenelzine), or ticlopidine because they may increase the risk of naltrexone's side effects
Opioid medicines (eg, methadone) or partial opioid agonists (eg, buprenorphine) because their effectiveness may be decreased by Dependex
Carbamazepine, efavirenz, lopinavir, phenobarbital, phenytoin, or ritonavir because they may decrease naltrexone's effectiveness
Amiloride, beta-blockers (eg, metoprolol, pindolol), certain antiarrhythmics (eg, flecainide, procainamide, propafenone), cimetidine, dopamine, famotidine, lorcaserin, memantine, metformin, oxaliplatin, phenothiazines (eg, thioridazine), ranitidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), tricyclic antidepressants (eg, nortriptyline), or varenicline because the risk of their side effects may be increased by Dependex
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dependex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How should I take Dependex?
Use Dependex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Dependex comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Dependex refilled.
Take Dependex by mouth with or without food. Avoid taking Dependex with high-fat meals.
Swallow Dependex whole. Do not break, crush, divide, or chew before swallowing. If you cannot swallow Dependex whole, contact your doctor.
Continue to take Dependex even if you feel well. Do not miss any doses.
If you miss a dose of Dependex, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Dependex.
Can Dependex be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Dependex be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Dependex, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Dependex. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
Patient reports
Patient reported useful
No survey data has been collected yet
Patient reported side effects
No survey data has been collected yet
One patient reported price estimates
Do you think The Price of Dependex is Worth It? Do you feel you paid higher than the value you got from it after usage? According to reports from gmedication.com users, on whether the Dependex medicine is affordable, users shared different opinions on the question. The views concerning the price of the medicine were based on some factors like the brand the patient bought, the price compared to its level of effectiveness, the nation or country where the medicine is sold, and the amount of money the patient has. For users who are of the opinion that the medicine is unaffordable, they may have to consider a medicine with another brand in a bid to reduce cost.
Patients
%
Expensive
1
100.0%
One patient reported frequency of use
How often should I take Dependex? According to the survey, gmedication.com reported that users of Dependex should take Twice in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Patients
%
Twice in a day
1
100.0%
Two patients reported doses
What is the specific doses you have used? Dependex May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients
%
11-50mg
2
100.0%
Patient reported time for results
No survey data has been collected yet
Patient reported administration
No survey data has been collected yet
Patient reported age
No survey data has been collected yet
Patient reviews
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