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What is denosumab 120 MG in 1.7 ML Injection

denosumab 120 MG in 1.7 ML Injection is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.
The Denosumab 120 MG in 1.7 ML Injection brand of denosumab 120 MG in 1.7 ML Injection is used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. denosumab 120 MG in 1.7 ML Injection is not for use in people with multiple myeloma (bone marrow cancer).
denosumab 120 MG in 1.7 ML Injection is also used to treat giant cell bone tumor in adults and teenagers with fully matured bone structure.
denosumab 120 MG in 1.7 ML Injection is also used to treat high blood levels of calcium caused by cancer, when other medicines such as pamidronate or zoledronic acid (Zometa) have been used without success.
denosumab 120 MG in 1.7 ML Injection guide provides information about the denosumab 120 MG in 1.7 ML Injection brand of denosumab 120 MG in 1.7 ML Injection. denosumab 120 MG in 1.7 ML Injection is another brand of denosumab 120 MG in 1.7 ML Injection used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.
denosumab 120 MG in 1.7 ML Injection may also be used for purposes not listed in denosumab 120 MG in 1.7 ML Injection guide.

How is denosumab 120 MG in 1.7 ML Injection given?

denosumab 120 MG in 1.7 ML Injection is injected under the skin of your stomach, upper thigh, or upper arm. A healthcare provider will give you this injection.
denosumab 120 MG in 1.7 ML Injection is usually given once every 4 weeks. Follow your doctor's instructions.
Your doctor may have you take extra calcium and vitamin D while you are being treated with denosumab 120 MG in 1.7 ML Injection. Take only the amount of calcium and vitamin D that your doctor has prescribed.
If you need to have any dental work, tell the dentist ahead of time that you are receiving denosumab 120 MG in 1.7 ML Injection. You may need to stop using the medicine for a short time.
Pay special attention to your dental hygiene. Brush and floss your teeth regularly while receiving denosumab 120 MG in 1.7 ML Injection. You may need to have a dental exam before you begin treatment with denosumab 120 MG in 1.7 ML Injection. Follow your doctor's instructions.

Denosumab 120 MG in 1.7 ML Injection side effects

Get emergency medical help if you have any of these signs of an allergic reaction: itching, rash, hives; difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Denosumab 120 MG in 1.7 ML Injection dosing

Usual Adult Dose for Osteoporosis:

Prolia: 60 mg subcutaneously once every 6 months
Comments:
-If a dose is missed, the injection should be administered as soon as the patient is available. Thereafter, injections should be scheduled every 6 months from the date of the last injection.
Uses:
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Treatment to increase bone mass in men with osteoporosis
-Treatment of bone loss in men receiving androgen deprivation therapy for prostate cancer
-Treatment of bone loss in women receiving adjuvant aromatase inhibitor therapy for breast cancer

Usual Adult Dose for Giant Cell Tumor of Bone:

denosumab 120 MG in 1.7 ML Injection (R): Initial dose: 120 mg subcutaneously on Days 8 and 15 of the first month of therapy in the upper arm, upper thigh, or abdomen
Maintenance dose: 120 mg subcutaneously every 4 weeks in the upper arm, upper thigh, or abdomen
Comments:
-Calcium and vitamin D should be administered to treat or prevent hypocalcemia.
Use: Treatment of adults and skeletally mature adolescents with giant cell tumor of bone that is unresectable or where surgical resection is likely to result in severe morbidity.

Usual Adult Dose for Osteolytic Bone Metastases of Solid Tumors:

Xgeva: 120 mg subcutaneously every 4 weeks
Comments:
-Calcium and vitamin D should be administered to treat or prevent hypocalcemia.
Use: Prevention of skeletal-related events in patients with bone metastases from solid tumors

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
XGEVA 120MG INJECTION 1 vial(s) (1 injection each) $383.83Glaxo SmithKline Pharmaceuticals Ltd
Xgeva 120mg Injection $403.02Glaxo SmithKline Pharmaceuticals Ltd

References

  1. Dailymed."Xgeva (denosumab) injection [amgen inc]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Denosumab". https://pubchem.ncbi.nlm.nih.gov/su... (accessed August 28, 2018).
  3. "Denosumab - drugbank". http://www.drugbank.ca/drugs/DB0664... (accessed August 28, 2018).

Denosumab 120 MG in 1.7 ML Injection - Frequently asked Questions

Can Denosumab 120 MG in 1.7 ML Injection be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect denosumab 120 MG in 1.7 ML Injection?

Other drugs may interact with denosumab 120 MG in 1.7 ML Injection, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

How should I take denosumab 120 MG in 1.7 ML Injection?

This medication guide provides information about the denosumab 120 MG in 1.7 ML Injection brand of denosumab 120 MG in 1.7 ML Injection. denosumab 120 MG in 1.7 ML Injection is another brand of denosumab 120 MG in 1.7 ML Injection used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.

You should not receive denosumab 120 MG in 1.7 ML Injection if you have low levels of calcium in your blood.

Who should not take denosumab 120 MG in 1.7 ML Injection?

You should not receive denosumab 120 MG in 1.7 ML Injection if you are allergic to it or if you have low levels of calcium in your blood (hypocalcemia).

While you are receiving denosumab 120 MG in 1.7 ML Injection, you should not use denosumab 120 MG in 1.7 ML Injection, another brand of denosumab 120 MG in 1.7 ML Injection.

To make sure denosumab 120 MG in 1.7 ML Injection is safe for you, tell your doctor if you have kidney disease (or if you are on dialysis).

denosumab 120 MG in 1.7 ML Injection may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, gum infection, or slow healing after dental work.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

FDA pregnancy category D. Do not use denosumab 120 MG in 1.7 ML Injection if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of denosumab 120 MG in 1.7 ML Injection on the baby.

It is not known whether denosumab 120 MG in 1.7 ML Injection passes into breast milk or if it could harm a nursing baby. However, this medication may slow the production of breast milk. You should not breast-feed while receiving denosumab 120 MG in 1.7 ML Injection.

Can Denosumab 120 MG in 1.7 ML Injection be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Denosumab 120 MG in 1.7 ML Injection be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Denosumab 120 MG in 1.7 ML Injection, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Denosumab 120 MG in 1.7 ML Injection. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology