RUBRAMIN PC® Cyanocobalamin Injection USP Rubramin PC (Cyanocobalamin Injection) contains Cyanocobalamin (vitamin B12) in a clear, red, sterile, nonpyrogenic, aqueous solution in a potency of 1000 mcg/mL (cobalt: 40 mcg/mL) for intramuscular use. Each mL of solution also contains 10 mg benzyl alcohol as a preservative and sodium chloride for isotonicity; pH has been adjusted between 4.5 and 7.0 with sodium hydroxide or hydrochloric acid. Cyanocobalamin is very hygroscopic in the anhydrous form, and sparingly soluble in water (1:80). The vitamin B12 coenzymes are very unstable in light. Rubramin PC is indicated for use as the flushing dose in the Schilling (vitamin B12 absorption) Test for pernicious anemia.
Hydroxocobalamin is a natural form of vitamin B12, prescribed for anemia and vitamin B12 deficiency.
Hydroxocobalamin indications
Hydroxocobalamin is a natural form of vitamin B12, prescribed for anemia and vitamin B12 deficiency. It works by increasing the level of vitamin B12 in conditions in which it is needed.
Hydroxocobalamin contraindication
Hypersensitivity.
Hydroxocobalamin dosage
The recommended initial dose for adults is 5g administered as an intravenous infusion over 15 minutes.
Hydroxocobalamin usage
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Hydroxocobalamin precautions
Caution should be exercised in patients with history of any allergy, who are taking other medications, during pregnancy and breastfeeding.
Hydroxocobalamin side effects
Most Common - Redness of the skin, rash, high blood pressure, nausea, headache and injection site pain. Eye - Swelling, irritation and redness. Gastrointestinal - Difficulty in swallowing, abdominal discomfort, vomiting, diarrhea, indigestion and lower gastrointestinal bleeding. General - Swelling in the extremities and chest discomfort. Immune system - Allergic reaction. Central Nervous system - Memory impairment, dizziness, and restlessness. Respiratory - Difficulty in breathing, throat tightness and dry throat. Skin - Hives and itching. Miscellaneous - Hot flush.
Hydroxocobalamin warning
Avoid excess dosage.
Hydroxocobalamin storage conditions
Store at 25°C.
Active ingredients: Cyanocobalamin/Hydroxocobalamin
Can Cyanocobalamin/Hydroxocobalamin be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Can Cyanocobalamin/Hydroxocobalamin be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Cyanocobalamin/Hydroxocobalamin be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Following the study conducted by gmedication.com on Cyanocobalamin/Hydroxocobalamin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Cyanocobalamin/Hydroxocobalamin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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