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What is 0.51 ML Enbrel 50 MG/ML Prefilled Syringe

0.51 ML Enbrel 50 MG/ML Prefilled Syringe works by decreasing a certain protein produced by the immune system. The immune system helps the body fight infections. In people with autoimmune disorders, the immune system mistakes the body's own cells for invaders and attacks them.
0.51 ML Enbrel 50 MG/ML Prefilled Syringe is used to treat the symptoms of rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, and to prevent joint damage caused by these conditions. It is also used to treat plaque psoriasis in adults and polyarticular juvenile idiopathic arthritis in children who are at least 2 years old.
0.51 ML Enbrel 50 MG/ML Prefilled Syringe may also be used for purposes not listed in 0.51 ML Enbrel 50 MG/ML Prefilled Syringe guide.

0.51 ML Enbrel 50 MG/ML Prefilled Syringe side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe and call your doctor right away if you have any of these symptoms of lymphoma:

Stop using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe and call your doctor at once if you have any of these other serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

0.51 ML Enbrel 50 MG/ML Prefilled Syringe dosing

Usual Adult Dose for Ankylosing Spondylitis:

25 mg subcutaneously twice weekly, 3 to 4 days apart. Alternatively, 50 mg subcutaneous doses may be given once a week on the same day.

Usual Adult Dose for Rheumatoid Arthritis:

25 mg subcutaneously twice weekly, 3 to 4 days apart. Alternatively, 50 mg subcutaneous doses may be given once a week on the same day.

Usual Adult Dose for Wegener's Granulomatosus:

25 mg subcutaneously twice weekly, 3 to 4 days apart. Alternatively, 50 mg subcutaneous doses may be given once a week on the same day.

Usual Adult Dose for Psoriatic Arthritis:

25 mg subcutaneously twice weekly, 3 to 4 days apart. Alternatively, 50 mg subcutaneous doses may be given once a week on the same day.

Usual Adult Dose for Still's Disease:

Study
25 mg subcutaneously, twice to three times per week.

Usual Adult Dose for SAPHO Syndrome:

Case (n=1)
25 mg subcutaneously twice weekly, along with corticosteroid therapy.

Usual Adult Dose for Psoriasis:

Plaque Psoriasis:
Initial: 50 mg subcutaneously twice weekly for 3 months. Alternatively, starting doses of 25 mg to 50 mg per week have been shown to be effective.
Maintenance: 50 mg subcutaneously once weekly.

Usual Pediatric Dose for Uveitis:

3 years or older: 0.4 mg/kg/dose (to a maximum of 25 mg) subcutaneously, twice weekly.

Usual Pediatric Dose for Histiocytosis:

Case
5 months or older: 0.4 mg/kg subcutaneously three times weekly.

Usual Pediatric Dose for Macrophage Activation Syndrome:

Case (n=1)
7 years or older: 0.4 mg/kg/dose subcutaneously twice weekly, for 11 weeks.

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

4 years or older: 0.8 mg/kg/week subcutaneously.
Child weight 31 to 62 kg (68 to 136 pounds): the total weekly dose should be administered as two (subcutaneous) injections, either on the same day or 3 to 4 days apart.
Child weight less than 31 kg (68 pounds): the dose should be administered as a single subcutaneous injection once weekly.
The maximum dose injected per site should not exceed 25 mg (1 mL).

Usual Pediatric Dose for Juvenile Idiopathic Arthritis:

Age 2 to 17 years with active polyarticular-course JIA:
Twice weekly dosing: 0.4 mg/kg/dose twice weekly given 72 to 96 hours apart
Maximum dose: 25 mg
Alternative once weekly dosing: 0.8 mg/kg/dose once weekly
Maximum: 50 mg per week
The 25 mg prefilled syringe is not recommended for pediatric patients weighing less than 31 kg (68 pounds). The 50 mg prefilled syringe or 0.51 ML Enbrel 50 MG/ML Prefilled Syringe (TM) auto-injector may be used for pediatric patients weighing 63 kg (138 pounds) or more.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
25 mg1 kit$1.00Canada, Mauritius, Singapore, Turkey, UK, USA
25 mg4 $1.00Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
25 mg4 $1.00Canada, India, NZ, Singapore, Turkey, UK, USA
25 mg4 $792.00
50 mg x 1 mL x 1's $220.65
ENBREL inj 25 mg x 0.5 mL x 0.5ml $111.76Wyeth
Enbrel inj 25 mg/0.5 mL (pre-filled syringe) 4 x 1's $763.23Pfizer

References

  1. Dailymed."Enbrel (etanercept) solution enbrel (etanercept) kit [immunex corporation]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Etanercept". https://pubchem.ncbi.nlm.nih.gov/su... (accessed August 28, 2018).
  3. "Etanercept - drugbank". http://www.drugbank.ca/drugs/DB0000... (accessed August 28, 2018).

0.51 ML Enbrel 50 MG/ML Prefilled Syringe - Frequently asked Questions

Can 0.51 ML Enbrel 50 MG/ML Prefilled Syringe be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take 0.51 ML Enbrel 50 MG/ML Prefilled Syringe?

You should not use this medication if you are allergic to 0.51 ML Enbrel 50 MG/ML Prefilled Syringe, or if you have a severe infection such as sepsis (infection of the blood).

Some people using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe have developed a rare fast-growing type of lymphoma (cancer). This condition affects the liver, spleen, and bone marrow, and it can be fatal. This has occurred mainly in teenagers and young adults using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe or similar medicines to treat Crohn's disease or ulcerative colitis. However, people with autoimmune disorders (including psoriasis) may have a higher risk of lymphoma. Talk to your doctor about your individual risk.

Before using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe, tell your doctor if you have ever had tuberculosis, if anyone in your household has tuberculosis, or if you have recently traveled to an area where tuberculosis is common.

To make sure you can safely use 0.51 ML Enbrel 50 MG/ML Prefilled Syringe, tell your doctor if you have any of these other conditions:

FDA pregnancy category B. 0.51 ML Enbrel 50 MG/ML Prefilled Syringe is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether 0.51 ML Enbrel 50 MG/ML Prefilled Syringe passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Children using this medication should be current on all childhood immunizations before starting treatment with 0.51 ML Enbrel 50 MG/ML Prefilled Syringe.

How should I take 0.51 ML Enbrel 50 MG/ML Prefilled Syringe?

Before you start treatment with 0.51 ML Enbrel 50 MG/ML Prefilled Syringe, your doctor may perform tests to make sure you do not have tuberculosis or other infections. Some infections are more likely to occur in certain areas of the world. Tell your doctor where you live and where you have recently traveled or plan to travel to during treatment.

0.51 ML Enbrel 50 MG/ML Prefilled Syringe is injected under the skin. You may be shown how to use injections at home. Do not self inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes. You may need to mix 0.51 ML Enbrel 50 MG/ML Prefilled Syringe with a liquid before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

A child must weigh at least 138 pounds to use the 0.51 ML Enbrel 50 MG/ML Prefilled Syringe autoinjector. Children who weigh less than 138 pounds should use a different form of 0.51 ML Enbrel 50 MG/ML Prefilled Syringe.

Use a different place on your body each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row. Avoid injecting into skin that is bruised, tender, red, or hard.

You may have pain, redness, swelling, or warmth where the medicine was injected. Call your doctor if these symptoms continue for longer than 5 days.

Use each disposable needle only one time. A single-use prefilled syringe or 0.51 ML Enbrel 50 MG/ML Prefilled Syringe autoinjector is for one injection only. Throw the used syringe or autoinjector away after one use, even if there is still medicine left in it. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

0.51 ML Enbrel 50 MG/ML Prefilled Syringe can lower blood cells that help your body fight infections. Your blood may need to be tested often. Serious and sometimes fatal infections may occur during treatment with 0.51 ML Enbrel 50 MG/ML Prefilled Syringe. Contact your doctor right away if you have signs of infection such as: fever, cough, sweating, tired feeling, or if you feel short of breath.

If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe. Visit your doctor regularly.

If you need surgery, tell the surgeon ahead of time that you are using 0.51 ML Enbrel 50 MG/ML Prefilled Syringe.

Store this medication in the refrigerator. Do not freeze. After mixing 0.51 ML Enbrel 50 MG/ML Prefilled Syringe with a diluent, store in the refrigerator and use it within 14 days. Do not use 0.51 ML Enbrel 50 MG/ML Prefilled Syringe after the expiration date on the label has passed.

Do not shake the prefilled syringe. Vigorous shaking can ruin the medicine. Do not use the medication if it has changed colors or appears cloudy. Call your doctor for a new prescription.

What other drugs will affect 0.51 ML Enbrel 50 MG/ML Prefilled Syringe?

Tell your doctor about all other medications you use, especially:

This list is not complete and there may be other drugs that can interact with 0.51 ML Enbrel 50 MG/ML Prefilled Syringe. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Can 0.51 ML Enbrel 50 MG/ML Prefilled Syringe be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can 0.51 ML Enbrel 50 MG/ML Prefilled Syringe be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on 0.51 ML Enbrel 50 MG/ML Prefilled Syringe, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of 0.51 ML Enbrel 50 MG/ML Prefilled Syringe. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology